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Substance Name: Clofarabine [USAN:INN:BAN]
RN: 123318-82-1
UNII: 762RDY0Y2H
InChIKey: WDDPHFBMKLOVOX-AYQXTPAHSA-N
Note
- An adenine arabinonucleoside derivative that acts as an antineoplastic antimetabolite. It is used in the treatment of ACUTE LYMPHOID LEUKEMIA in pediatric patients who have relapsed.
Molecular Formula
- C10-H11-Cl-F-N5-O3
Molecular Weight
- 303.6799
Classification Codes
- Antimetabolites
- Antimetabolites, Antineoplastic
- Antineoplastic Agents
- Mutation Data
- Noxae
- Treatment of Primary Refractory or Relapsed Acute Myelogenous Leukemia (AML) or Acute Lymphoblastic Leukemia (ALL) in Pediatric and Adult Patients
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Names and Synonyms
Name of Substance
- Clofarabine
- Clofarabine [USAN:INN:BAN]
MeSH Heading
- Clofarabine
Synonyms
- 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine
- 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine
- C1-F-Ara-A
- Clofarabine
- Clofarex
- Clolar
- Evoltra
- NSC 759857
- UNII-762RDY0Y2H
Systematic Names
- 2-Chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-9H-purin-6-amine
- 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-
Registry Numbers
CAS Registry Number
- 123318-82-1
FDA UNII
- 762RDY0Y2H
System Generated Number
- 0123318821