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Substance Name: Lymecycline [INN:BAN]
RN: 992-21-2
UNII: 7D6EM3S13P
InChIKey: AHEVKYYGXVEWNO-UEPZRUIBSA-N
Note
- A semisynthetic antibiotic related to TETRACYCLINE. It is more readily absorbed than TETRACYCLINE and can be used in lower doses.
Molecular Formula
- C29-H38-N4-O10
Molecular Weight
- 602.6372
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Drug / Therapeutic Agent
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Names and Synonyms
Name of Substance
- Lymecycline
- Lymecycline [INN:BAN]
MeSH Heading
- Lymecycline
Synonyms
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, lysinemethylene deriv.
- Armyl
- Ciclisin
- Ciclolysal
- EINECS 213-592-2
- Infaciclina
- Limeciclina
- Limeciclina [INN-Spanish]
- Lisinbiotic
- Lymecycline
- Lymecyclinum
- Lymecyclinum [INN-Latin]
- Mucomycin
- N(sup 2)-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline
- N-Lysinomethyltetracycline
- N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido)methyl)lysine
- Tetraciclina-L-metilenlisina
- Tetraciclina-L-metilenlisina [Italian]
- Tetracycline, lysinomethyl-
- Tetracycline-L-methylene lysine
- Tetracycline-L-methylenelysine
- Tetralisal
- Tetralysal
- UNII-7D6EM3S13P
- Vebicyclysal
Systematic Names
- (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide
- L-Lysine, N6-(((((4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl)carbonyl)amino)methyl)-
- L-Lysine, N6-((((4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl)carbonyl)amino)methyl)-, (4S-(4alpha,4aalpha,6beta,12aalpha))-
- Lymecycline
- Lysine, N(sup 6)-((4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamido)methyl)-, (+)-
Registry Numbers
CAS Registry Number
- 992-21-2
FDA UNII
- 7D6EM3S13P
Other Registry Numbers
- 15302-19-9
- 31041-50-6
- 8059-91-4
System Generated Number
- 0000992212
Structure Descriptors
InChI
InChI=1S/C29H38N4O10/c1-28(42)13-7-6-9-17(34)18(13)22(35)19-14(28)11-15-21(33(2)3)23(36)20(25(38)29(15,43)24(19)37)26(39)32-12-31-10-5-4-8-16(30)27(40)41/h6-7,9,14-16,21,31,34,36-37,42-43H,4-5,8,10-12,30H2,1-3H3,(H,32,39)(H,40,41)/t14-,15-,16-,21-,28+,29-/m0/s1InChIKey
AHEVKYYGXVEWNO-UEPZRUIBSA-NSmiles
CN(C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mammal (species unspecified) | LD50 | unreported | 253mg/kg (253mg/kg) | British Medical Journal. Vol. 2, Pg. 106, 1964. | |
mouse | LD50 | intravenous | 181mg/kg (181mg/kg) | Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 333, 1970. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | -3.220 | (none) | EST | |
Atmospheric OH Rate Constant | 4.11E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.