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Substance Name: Zolpidem [INN:BAN]
RN: 82626-48-0
UNII: 7K383OQI23
InChIKey: ZAFYATHCZYHLPB-UHFFFAOYSA-N

Notes

  • A nonbenzodiazepine; benzodiazepine receptor agonist; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors.
  • Benzodiazepine receptor agonist.

Molecular Formula

  • C19-H21-N3-O

Molecular Weight

  • 307.3949
 

Classification Codes

Classification Codes

  • Central Nervous System Agents
  • Central Nervous System Depressants
  • GABA Agents
  • GABA Agonists
  • GABA-A Receptor Agonists
  • Hypnotics and Sedatives
  • Neurotransmitter Agents
  • Sleep Aids, Pharmaceutical

Superlist Classification Code

  • DEA Schedule IV

Names and Synonyms

Name of Substance

  • Zolpidem
  • Zolpidem [INN:BAN]

MeSH Heading

  • Zolpidem

Synonyms

  • Lorex
  • N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide
  • SL 80-0750
  • SL 800750
  • SL800750
  • UNII-7K383OQI23
  • Zolpidem
  • Zolpidemum
  • Zolpidemum [Latin]

Systematic Name

  • Imidazo(1,2-a)pyridine-3-acetamide, N,N,6-trimethyl-2-(4-methylphenyl)-

Superlist Names

  • DEA No. 2783
  • Zolpidem

Registry Numbers

CAS Registry Number

  • 82626-48-0

FDA UNII

  • 7K383OQI23

System Generated Number

  • 0082626480

Structure Descriptors

InChI

InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3

InChIKey

ZAFYATHCZYHLPB-UHFFFAOYSA-N

Smiles

CN(C)C(=O)Cc1c(nc2ccc(C)cn12)c3ccc(C)cc3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 200ug/kg (0.2mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" Journal of Clinical Psychiatry. Vol. 56, Pg. 35, 1995.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 196 deg C   EXP
pKa Dissociation Constant 6.2 (none)   EXP
log P (octanol-water) 3.850 (none)   EST
Atmospheric OH Rate Constant 1.46E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.