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Substance Name: Pramipexole [USAN:INN:BAN]
RN: 104632-26-0
UNII: 83619PEU5T


  • A benzothiazole derivative and dopamine agonist with antioxidant properties that is used in the treatment of PARKINSON DISEASE and RESTLESS LEGS SYNDROME.
  • Pramipexole is used alone or with other medications to treat the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance), including shaking of parts of the body, stiffness, slowed movements, and problems with balance. Pramipexole is also used to treat restless legs syndrome (RLS; a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down). Pramipexole is in a class of medications called dopamine agonists. It works by acting in place of dopamine, a natural substance in the brain that is needed to control movement.

Molecular Formula

  • C10-H17-N3-S

Molecular Weight

  • 211.3313

Classification Codes

  • Anti-Dyskinesia Agents
  • Antidepressant
  • Antioxidants
  • Antiparkinson Agents
  • Antiparkinsonian
  • Antischizophrenic
  • Central Nervous System Agents
  • Dopamine Agents
  • Dopamine Agonist
  • Dopamine Agonists
  • Neurotransmitter Agents
  • Protective Agents

Names and Synonyms

Name of Substance

  • Pramipexole
  • Pramipexole [USAN:INN:BAN]

MeSH Heading

  • Pramipexole


  • (-)-Pramipexole
  • 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-
  • EC 600-593-1
  • HSDB 8253
  • KNS-760704
  • Mirapexin
  • NSC 760426
  • Oprymea
  • Pramipexol
  • Pramipexol [Spanish]
  • Pramipexole
  • Pramipexole Teva
  • Pramipexolum
  • Pramipexolum [Latin]
  • Sifrol
  • SND 919
  • SUD 919CL2Y
  • SUD919CL2Y
  • U-98528E
  • UNII-83619PEU5T

Systematic Names

  • (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole
  • (S)-2-Amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole
  • 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (S)-

Registry Numbers

CAS Registry Number

  • 104632-26-0


  • 83619PEU5T

System Generated Number

  • 0104632260

Structure Descriptors