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Substance Name: Povidone-iodine [USP:BAN:JAN]
RN: 25655-41-8
UNII: 85H0HZU99M
Note
- An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol. The iodine may be radiolabeled for research purposes.
Molecular Formula
- (C6-H9-N-O)x-.x-I2
Molecular Weight
- 364.9431
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
Classification Codes
- Anti-Infective Agents
- Anti-Infective Agents, Local
- Anti-Infective, Topical
- Antiviral (COVID-19)
- Drug / Therapeutic Agent
- Human Data
- Mutation Data
- Reproductive Effect
- Skin / Eye Irritant
- TSCA Flag XU (Exempt from Reporting under Chemical Data Reporting Rule)
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Links to Resources
NLM Resources (File Locators)
Regulatory Agencies (Superlist Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- 1-Vinyl-2-pyrrolidinone polymer W/iodine
- 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine
- Polyvinylpyrrolidone-iodine complex
- Povidone-iodine
- Povidone-iodine [USP:BAN:JAN]
- PVP-Iodine
MeSH Heading
- Povidone-iodine
Synonyms
- 1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine
- 1-Vinyl-2-pyrrolidinone polymer, compd. with iodine
- 1-Vinyl-2-pyrrolidinone polymer, compound with iodine
- 1-Vinyl-2-pyrrolidinone polymers, iodine complex
- 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine
- Argentyne
- Betadin
- Betadine
- Betadine (VAN)
- Betaisodona
- Braunol
- Braunosan H
- Bridine
- CCRIS 9290
- Disadine D.P.
- Disphex
- E-Z Prep
- E-Z Prep 220
- E-Z Scrub
- E-Z Scrub 201
- E-Z Scrub 241
- Efo-dine
- HSDB 6831
- Inadine
- Iodinated poly(vinylpyrrolidone)
- Iodine-poly(vinylpyrrolidinone)
- Iodine-polyvinylpyrrolidone complex
- Iodopoly(vinyl pyrrolidinone)
- Isobetadyne
- Isodine
- NSC 26245
- Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex
- Poly(vinylpyrrolidinone) iodide
- Poly(vinylpyrrolidinone)-iodine complex
- Poly(vinylpyrrolidone) - iodine complex
- Poly(vinylpyrrolidone)-iodine adduct
- Polyvinylpyrrolidone compound with iodine
- Polyvinylpyrrolidone-iodine complex
- Povadyne
- Povidone iodine
- Povidone-iodine
- Povidone-lodine
- Proviodine
- PVP iodine
- Pvp-1
- PVP-I
- PVP-Iodine
- PVP-Iodine, 30-06
- Traumasept
- Ultradine
- UNII-85H0HZU99M
- Videne
Systematic Names
- 2-Pyrrolidinone, 1-ethenyl-, homopolymer, compd. with iodine
- 2-Pyrrolidinone, 1-vinyl-, polymers, compd. with iodine
- Poly(1-(2-oxo-1-pyrrolidinyl)ethylene)iodine complex
Superlist Name
- Polyvinylpyrrolidone - iodine complex
Registry Numbers
CAS Registry Number
- 25655-41-8
FDA UNII
- 85H0HZU99M
Other Registry Numbers
- 113813-78-8
- 1202865-55-1
- 1216458-36-4
- 1219590-00-7
- 1246654-78-3
- 129947-86-0
- 130095-86-2
- 138115-12-5
- 180749-13-7
- 26856-09-7
- 30849-75-3
- 36703-90-9
- 9006-37-5
- 94555-99-4
System Generated Number
- 0025655418
Molecular Formulas
Molecular Formula
- (C6-H9-N-O)x-.x-I2
Molecular Formula Fragments
- C6-H9-N-O
- COMPONENT
- I
Structure Descriptors
Smiles
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| human | TDLo | skin | 3400mg/kg/24H (3400mg/kg) | BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | JAMA, Journal of the American Medical Association. Vol. 240, Pg. 249, 1978. |
| mouse | LD50 | intravenous | 480mg/kg (480mg/kg) | Drugs in Japan Vol. 6, Pg. 788, 1982. | |
| mouse | LD50 | oral | 8100mg/kg (8100mg/kg) | Drugs in Japan Vol. 6, Pg. 788, 1982. | |
| mouse | LD50 | subcutaneous | 4100mg/kg (4100mg/kg) | Drugs in Japan Vol. 6, Pg. 788, 1982. | |
| rat | LD50 | intravenous | 640mg/kg (640mg/kg) | Drugs in Japan Vol. 6, Pg. 788, 1982. | |
| rat | LD50 | oral | > 8gm/kg (8000mg/kg) | Drugs in Japan Vol. 6, Pg. 788, 1982. | |
| rat | LD50 | subcutaneous | 3450mg/kg (3450mg/kg) | Drugs in Japan Vol. 6, Pg. 788, 1982. |