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Substance Name: Imatinib mesylate [USAN]
RN: 220127-57-1
UNII: 8A1O1M485B
InChIKey: YLMAHDNUQAMNNX-UHFFFAOYSA-N
Note
- A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.
Molecular Formula
- C29-H31-N7-O.C-H4-O3-S
Molecular Weight
- 589.7175
Classification Codes
- Anti-Leukemia and Anti-Tumor Agent (Tyrosine Kinase Inhibitor)
- Antineoplastic
- Antineoplastic Agents
- Antiviral (COVID-19)
- Enzyme Inhibitors
- Protein Kinase Inhibitors
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Names and Synonyms
Name of Substance
- Imatinib mesylate
- Imatinib mesylate [USAN]
MeSH Heading
- Imatinib Mesylate
Synonyms
- CGP 57148B
- Gleevec
- Glivec
- HSDB 7142
- Imatinib mesilate
- Imatinib mesylate
- Imatinib methanesulfonate
- Imatinib monomethanesulfonate
- NSC 716051
- Shantinib
- STI 571
- STI571
- UNII-8A1O1M485B
Systematic Name
- Benzamide, 4-((4-methyl-1-piperazinyl)methyl)-N-(4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)phenyl)-, monomethanesulfonate
Registry Numbers
CAS Registry Number
- 220127-57-1
FDA UNII
- 8A1O1M485B
System Generated Number
- 0220127571
Molecular Formulas
Molecular Formula
- C29-H31-N7-O.C-H4-O3-S
Molecular Formula Fragments
- C-H4-O3-S
- C29-H31-N7-O
- COMPONENT