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Substance Name: Lobucavir [USAN:INN]
RN: 127759-89-1
UNII: 8U5PYQ1R2E
InChIKey: GWFOVSGRNGAGDL-FSDSQADBSA-N
Note
- Inhibits the replication of HIV virus in T cells, monocytes & macrophages in vitro by inhibiting DNA polymerase and viral DNA synthesis.
Molecular Formula
- C11-H15-N5-O3
Molecular Weight
- 265.2715
Classification Codes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral
- Antiviral Agents
- Enzyme Inhibitors
- Nucleic Acid Synthesis Inhibitors
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Names and Synonyms
Name of Substance
- Lobucavir
- Lobucavir [USAN:INN]
Synonyms
- (+)-Cyclobut G
- 6H-Purin-6-one, 2-amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro, (1R-(1alpha,2beta,3alpha))
- 9-((1R,2R,3S)-2,3-Bis(hydroxymethyl)cyclobutyl)guanine
- A-69992
- BMS 180194
- BMS-180194
- C-Oxetanocin-G
- C-Oxt-G
- CCRIS 9309
- DRG-0235
- Lobucavir
- SQ 34,514
- SQ 34514
- UNII-8U5PYQ1R2E
Systematic Names
- 6H-Purin-6-one, 2-amino-9-((1R,2R,3S)-2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-
- 6H-Purin-6-one, 2-amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-, (1R-(1alpha,2beta,3alpha))-
Registry Numbers
CAS Registry Number
- 127759-89-1
FDA UNII
- 8U5PYQ1R2E
System Generated Number
- 0127759891