Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Halobetasol propionate [USAN:USP]
RN: 66852-54-8
UNII: 91A0K1TY3Z
InChIKey: BDSYKGHYMJNPAB-LICBFIPMSA-N

Note

  • Used in ointment to treat psoriasis; Ulobetasol cream contains 0.05% 6-fluoroclobetasol 17-propionate

Molecular Formula

  • C25-H31-Cl-F2-O5

Molecular Weight

  • 484.9639
 

Classification Codes

  • Anti-Inflammatory (Topical)
  • Drug / Therapeutic Agent
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Halobetasol
  • Halobetasol propionate [USAN:USP]

Synonyms

  • 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
  • BMY 30056
  • BMY-30056
  • CGP 14458
  • CGP-14,458
  • Halobetasol propionate
  • Ulobetasol propionate
  • Ultravate
  • UNII-91A0K1TY3Z

Systematic Name

  • Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6alpha,11beta,16beta)-

Superlist Name

  • Halobetasol propionate

Registry Numbers

CAS Registry Number

  • 66852-54-8

FDA UNII

  • 91A0K1TY3Z

System Generated Number

  • 0066852548

Structure Descriptors

InChI

1S/C25H31ClF2O5/c1-5-21(32)33-25(20(31)12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15-,16-,18-,19-,22-,23-,24-,25-/m0/s1

InChIKey

BDSYKGHYMJNPAB-LICBFIPMSA-N

Smiles

CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)CCl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral > 15mL/kg (15mL/kg)   Medicamentos de Actualidad. Vol. 27, Pg. 304, 1991.