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Substance Name: Tenofovir hydrate
RN: 206184-49-8
UNII: 99YXE507IL
InChIKey: PINIEAOMWQJGBW-FYZOBXCZSA-N

Note

  • An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.

Molecular Formula

  • C9-H14-N5-O4-P.H2-O

Molecular Weight

  • 305.2294
 

Classification Codes

  • Anti-HIV Agents
  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antiviral Agents
  • Enzyme Inhibitors
  • Nucleic Acid Synthesis Inhibitors
  • Reverse Transcriptase Inhibitors

Names and Synonyms

Results Name

  • Tenofovir hydrate

Name of Substance

  • Tenofovir
  • Tenofovir [USAN]

MeSH Heading

  • Tenofovir

Synonyms

  • Tenofovir
  • UNII-99YXE507IL

Systematic Name

  • Phosphonic acid, ((2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)-, monohydrate, (R)-

Registry Numbers

CAS Registry Number

  • 206184-49-8

FDA UNII

  • 99YXE507IL

System Generated Number

  • 0206184498

Molecular Formulas

Molecular Formula

  • C9-H14-N5-O4-P.H2-O

Molecular Formula Fragments

  • C9-H14-N5-O4-P
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

1S/C9H14N5O4P.H2O/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14;/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17);1H2/t6-;/m1./s1

InChIKey

PINIEAOMWQJGBW-FYZOBXCZSA-N

Smiles

C[C@H](Cn1cnc2c1ncnc2N)OCP(=O)(O)O.O