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Substance Name: Spermine hydrochloride
RN: 306-67-2
UNII: 9CI1570O48
InChIKey: XLDKUDAXZWHPFH-UHFFFAOYSA-N

Note

  • A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.

Molecular Formula

  • C10-H26-N4.4Cl-H

Molecular Weight

  • 348.187
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
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Names and Synonyms

Results Name

  • Spermine hydrochloride

Name of Substance

  • Spermine tetrahydrochloride

Synonyms

  • 1,4-Bis(aminopropyl)butanediamine tetrahydrochloride
  • 1,4-Butanediamino, N,N'-bis(3-aminopropyl), tetrahydrochloride
  • CCRIS 8452
  • EINECS 206-189-8
  • Gerontine tetrahydrochloride
  • Musculamine tetrahydrochloride
  • N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
  • Neuridine tetrahydrochloride
  • NSC 69852
  • Spermine HCl
  • Spermine hydrochloride
  • Spermine tetrahydrochloride
  • UNII-9CI1570O48

Systematic Names

  • 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-, tetrahydrochloride
  • 1,4-Butanediamine, N1,N4-bis(3-aminopropyl)-, hydrochloride (1:4)
  • 4,9-Diazoniadodecamethylenediammonium tetrachloride

Registry Numbers

CAS Registry Number

  • 306-67-2

FDA UNII

  • 9CI1570O48

System Generated Number

  • 0000306672

Molecular Formulas

Molecular Formula

  • C10-H26-N4.4Cl-H

Molecular Formula Fragments

  • C10-H26-N4
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H

InChIKey

XLDKUDAXZWHPFH-UHFFFAOYSA-N

Smiles

Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 370mg/kg (370mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 41, Pg. 1575, 1982.