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Substance Name: Cycasin
RN: 14901-08-7
UNII: 9H51HL0E1D
InChIKey: YHLRMABUJXBLCK-LBCXAKKBSA-N
Note
- Carcinogenic and neurotoxic glycoside occurring in a number of plant species, including Cycas revoluta.
Molecular Formula
- C8-H16-N2-O7
Molecular Weight
- 252.221
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- Physical Properties
Classification Codes
Classification Codes
- Carcinogens
- Mutation Data
- Natural Product
- Neurotoxins
- Noxae
- Reproductive Effect
- Tumor Data
Superlist Classification Code
- Overall Carcinogenic Evaluation: Group 2B
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Names and Synonyms
Name of Substance
- Cycasin
MeSH Heading
- Cycasin
Synonyms
- (Methyl-ONN-azoxy)-methyl-beta-D-glucopyranoside
- (Methyl-ONN-azoxy)methyl beta-D-glucopyranoside
- 4-17-00-03009 (Beilstein Handbook Reference)
- beta-D-Glucopyranoside, (methyl-ONN-azoxy)methyl
- beta-D-Glucosyloxyazoxymethane
- beta-D-Glucosyloxyazoxymethase
- BRN 0025396
- CCRIS 185
- Cycas revoluta glucoside
- Cycasin
- Cykazine
- HSDB 5096
- Methylazoxymethanol glucoside
- Methylazoxymethanol-beta-D-glucoside
- Methylazoxymethanolbeta-D-glucoside
- Methylazoxymethyl-b-D-glucopyranoside
- NSC 15190
- UNII-9H51HL0E1D
Systematic Names
- beta-D-Glucopyranoside, ((Z)-methyl-ONN-azoxy) methyl
- beta-D-Glucopyranoside, (methyl-ONN-azoxy)methyl-
- Cycasin
Superlist Names
- beta-D-Glucopyranoside, (methyl-ONN-azoxy)methyl-
- Cycasin
Registry Numbers
CAS Registry Number
- 14901-08-7
FDA UNII
- 9H51HL0E1D
System Generated Number
- 0014901087
Structure Descriptors
InChI
InChI=1S/C8H16N2O7/c1-10(15)9-3-16-8-7(14)6(13)5(12)4(2-11)17-8/h4-8,11-14H,2-3H2,1H3/b10-9-/t4-,5-,6+,7-,8-/m1/s1InChIKey
YHLRMABUJXBLCK-LBCXAKKBSA-NSmiles
C\[N+](=N\CO[C@@H]1O[C@H](CO)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 20mg/kg (20mg/kg) | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 31, Pg. 1493, 1972. | |
| hamster | LD50 | oral | 250mg/kg (250mg/kg) | BEHAVIORAL: ATAXIA | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 31, Pg. 1493, 1972. |
| mouse | LD50 | oral | 500mg/kg (500mg/kg) | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 31, Pg. 1493, 1972. | |
| rabbit | LD50 | oral | 30mg/kg (30mg/kg) | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 31, Pg. 1493, 1972. | |
| rat | LD50 | oral | 270mg/kg (270mg/kg) | Gann. Japanese Journal of Cancer Research. Vol. 62, Pg. 353, 1971. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| log P (octanol-water) | -2.660 | (none) | EST | |
| Atmospheric OH Rate Constant | 6.90E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.