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Substance Name: Oxymorphone [INN:BAN]
RN: 76-41-5


  • An opioid analgesic with actions and uses similar to those of MORPHINE, apart from an absence of cough suppressant activity. It is used in the treatment of moderate to severe pain, including pain in obstetrics. It may also be used as an adjunct to anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1092).

Molecular Formula

  • C17-H19-N-O4

Molecular Weight

  • 301.3401

Classification Codes

Classification Codes

  • Adjuvants, Anesthesia
  • Analgesics
  • Analgesics, Opioid
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Drug / Therapeutic Agent
  • Narcotics
  • Peripheral Nervous System Agents
  • Sensory System Agents

Superlist Classification Code

  • DEA Schedule II
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Names and Synonyms

Results Name

  • Oxymorphone [INN:BAN]

Name of Substance

  • Oxymorphone
  • Oxymorphone [INN:BAN]

MeSH Heading

  • Oxymorphone


  • (14S)-14-Hydroxydihydromorphinone
  • 14-Hydroxydihydromorphinone
  • 3,14-Dihydroxy-4,5-alpha-epoxy-17-methylmorphinan-6-one
  • 4-27-00-03681 (Beilstein Handbook Reference)
  • 7,8-Dihydro-14-hydroxymorphinone
  • BRN 0041588
  • Dihydro-14-hydroxymorphinone
  • Dihydrohydroxymorphinone
  • EINECS 200-959-7
  • HSDB 8060
  • Morphinone, dihydro-14-hydroxy-
  • NSC 19045
  • Numorphan
  • Ossimorfone
  • Ossimorfone [DCIT]
  • Oximorfona
  • Oximorfona [INN-Spanish]
  • Oximorphonum
  • Oxymorphone
  • Oxymorphonum
  • Oxymorphonum [INN-Latin]
  • UNII-9VXA968E0C

Systematic Names

  • Morphinan-6-one, 3,14-dihydroxy-4,5-alpha-epoxy-17-methyl-
  • Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-methyl-, (5-alpha)-
  • Morphinan-6-one, 4,5alpha-epoxy-3,14-dihydroxy-17-methyl-
  • Oxymorphone

Superlist Names

  • DEA No. 9652
  • Oxymorphone

Registry Numbers

CAS Registry Number

  • 76-41-5


  • 9VXA968E0C

Related Registry Number

  • 357-07-3 (hydrochloride)

System Generated Number

  • 0000076415

Structure Descriptors








Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 200mg/kg (200mg/kg)   Toxicology and Applied Pharmacology. Vol. 3, Pg. 261, 1961.
mouse LD50 intravenous 172mg/kg (172mg/kg)   Yakugaku Zasshi. Journal of Pharmacy. Vol. 84, Pg. 280, 1964.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 248-249 deg C   EXP
pKa Dissociation Constant 8.17 (none)   EXP
log P (octanol-water) 0.83 (none)   EXP
Water Solubility 2.40E+04 mg/L 25 EST
Vapor Pressure 2.63E-10 mm Hg 25 EST
Henry's Law Constant 4.09E-19 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.04E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.