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Substance Name: Pilsicainide [INN]
RN: 88069-67-4
UNII: AV0X7V6CSE
InChIKey: BCQTVJKBTWGHCX-UHFFFAOYSA-N

Classification Codes

  • Anti-Arrhythmia Agents
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Membrane Transport Modulators
  • Sodium Channel Blockers

Molecular Formula

  • C17-H24-N2-O

Molecular Weight

  • 272.39
 
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Names and Synonyms

Name of Substance

  • Pilsicainide
  • Pilsicainide [INN]

Synonyms

  • Pilsicainida
  • Pilsicainida [INN-Spanish]
  • Pilsicainide
  • Pilsicainidum
  • Pilsicainidum [INN-Latin]
  • Pilzicainide
  • UNII-AV0X7V6CSE

Systematic Names

  • 1H-Pyrrolizine-7a(5H)-acetamide, N-(2,6-dimethylphenyl)tetrahydro-
  • Tetrahydro-1H-pyrrolizine-7a(5H)-aceto-2',6'-xylidide

Registry Numbers

CAS Registry Number

  • 88069-67-4

FDA UNII

  • AV0X7V6CSE

System Generated Number

  • 0088069674

Structure Descriptors

InChI

InChI=1S/C17H24N2O/c1-13-6-3-7-14(2)16(13)18-15(20)12-17-8-4-10-19(17)11-5-9-17/h3,6-7H,4-5,8-12H2,1-2H3,(H,18,20)

InChIKey

BCQTVJKBTWGHCX-UHFFFAOYSA-N

Smiles

Cc1cccc(C)c1NC(=O)CC23CCCN2CCC3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 53mg/kg (53mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
mouse LD50 intraperitoneal 85mg/kg (85mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
mouse LD50 intravenous 17mg/kg (17mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
mouse LD50 oral 175mg/kg (175mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
rat LD50 intraperitoneal 105mg/kg (105mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
rat LD50 intravenous 18mg/kg (18mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.
rat LD50 oral 255mg/kg (255mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 769, 1991.