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Substance Name: Xylenes
RN: 1330-20-7
UNII: D856J1047R

Note

  • A family of isomeric, colorless aromatic hydrocarbon liquids, that contain the general formula C6H4(CH3)2. They are produced by the destructive distillation of coal or by the catalytic reforming of petroleum naphthenic fractions. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed).

Molecular Formula

  • C8-H10

Molecular Weight

  • 106.165
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Human Data
  • Mutation Data
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 58
  • 2011 CERCLA Priority List, Rank: 62
  • Overall Carcinogenic Evaluation: Group 3
  • Reportable Quantity (RQ) = 1000 lb
  • TWA (100 ppm); STEL (150 ppm); Not classifiable as a human carcinogen; BEI
  • TWA 100 ppm (435 mg/m3)

Names and Synonyms

Results Name

  • Xylenes

Name of Substance

  • Benzene, dimethyl-
  • Dimethylbenzene
  • Xylene
  • Xylenes

MeSH Heading

  • Xylenes

Synonyms

  • 4-05-00-00951 (Beilstein Handbook Reference)
  • AI3-02209-X
  • Benzene, dimethyl-
  • BRN 1901563
  • Caswell No. 906
  • CCRIS 903
  • Dimethylbenzene
  • EC 215-535-7
  • EINECS 215-535-7
  • EPA Pesticide Chemical Code 086802
  • HSDB 4500
  • Ksylen
  • Ksylen [Polish]
  • Methyl toluene
  • Methyltoluene
  • NCI-C55232
  • RCRA waste number U239
  • UN 1307
  • UNII-D856J1047R
  • Violet 3
  • Xiloli
  • Xiloli [Italian]
  • Xylene
  • Xylenen
  • Xylenen [Dutch]
  • Xylenes
  • Xylol
  • Xylole
  • Xylole [German]

Systematic Names

  • Benzene, dimethyl-
  • Xylene
  • Xylene, mixed isomers, pure
  • Xylenes (mixed)

Superlist Names

  • Benzene, dimethyl-
  • Dimethylbenzene
  • RCRA waste no. U239
  • Xylene
  • Xylene (mixed isomers)
  • Xylene, isomers
  • Xylene, mixed
  • Xylenes (isomers and mixture)
  • Xylenes (mixed)
  • Xylenes, total

Registry Numbers

CAS Registry Number

  • 1330-20-7

FDA UNII

  • D856J1047R

Other Registry Number

  • 8026-09-3

System Generated Number

  • 0001330207

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LCLo inhalation 450ppm (450ppm) LIVER: FATTY LIVER DEGERATION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Journal of Industrial Hygiene. Vol. 10, Pg. 261, 1928.
guinea pig LDLo intraperitoneal 2gm/kg (2000mg/kg) LIVER: FATTY LIVER DEGERATION American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974.
human LDLo oral 50mg/kg (50mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 883, 1980.
human TCLo inhalation 200ppm (200ppm) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES		 Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
mammal (species unspecified) LC50 inhalation 30gm/m3 (30000mg/m3)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LD50 oral 4300mg/kg (4300mg/kg)   Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified) LDLo intraperitoneal 2gm/kg (2000mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: IRRITABILITY

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 American Journal of Hygiene. Vol. 7, Pg. 276, 1927.
man LCLo inhalation 10000ppm/6H (10000ppm) BLOOD: OTHER CHANGES

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BEHAVIORAL: GENERAL ANESTHETIC		 British Medical Journal. Vol. 3, Pg. 442, 1970.
mouse LD50 intraperitoneal 1548mg/kg (1548mg/kg)   Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 18, Pg. 109, 1960.
mouse LD50 oral 2119mg/kg (2119mg/kg)   EHP, Environmental Health Perspectives. Vol. 106(Suppl,
rabbit LD50 skin > 1700mg/kg (1700mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.
rabbit LDLo intravenous 129mg/kg (129mg/kg)   Haematologica. Vol. 58, Pg. 491, 1973.
rat LC50 inhalation 5000ppm/4H (5000ppm)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.
rat LD50 intraperitoneal 2459mg/kg (2459mg/kg)   Environmental Research. Vol. 40, Pg. 411, 1986.
rat LD50 oral 4300mg/kg (4300mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

LIVER: OTHER CHANGES		 AMA Archives of Industrial Health. Vol. 14, Pg. 387, 1956.
rat LD50 subcutaneous 1700mg/kg (1700mg/kg)   Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 123, 1974.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Boiling Point 138.5 deg C   EXP
log P (octanol-water) 3.16 (none)   EXP
Water Solubility 106 mg/L 25 EXP
Vapor Pressure 7.99 mm Hg 25 EXP
Henry's Law Constant 0.00663 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.87E-11 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.