Skip Navigation
ChemIDplus Lite•Browse•Advanced

Substance Name: Dolutegravir [USAN:INN]
RN: 1051375-16-6
UNII: DKO1W9H7M1
InChIKey: RHWKPHLQXYSBKR-BMIGLBTASA-N

Note

  • An HIV-1 integrase inhibitor.

Molecular Formula

  • C20-H19-F2-N3-O5

Molecular Weight

  • 419.3821
 

Classification Codes

  • Anti-HIV Agents
  • Anti-Infective Agents
  • Anti-Retroviral Agents
  • Antiviral Agents
  • Enzyme Inhibitors
  • HIV Integrase Inhibitors
  • Integrase Inhibitors
  • Treatment of HIV Infection
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Dolutegravir [USAN:INN]

Synonyms

  • Dolutegravir
  • GSK 1349572
  • GSK-1349572
  • GSK1349572
  • HSDB 8152
  • S-349572
  • S-GSK1349572
  • S/GSK1349572
  • UNII-DKO1W9H7M1

Systematic Name

  • 2H-Pyrido(1',2':4,5)pyrazino(2,1-b)(1,3)oxazine-9-carboxamide, N-((2,4-difluorophenyl)methyl)-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-

Registry Numbers

CAS Registry Number

  • 1051375-16-6

FDA UNII

  • DKO1W9H7M1

Other Registry Number

  • 1172581-47-3

System Generated Number

  • 1051375166

Structure Descriptors

InChI

InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1

InChIKey

RHWKPHLQXYSBKR-BMIGLBTASA-N

Smiles

C[C@@H]1CCO[C@H]2CN3C=C(C(=O)NCc4ccc(F)cc4F)C(=O)C(=C3C(=O)N12)O