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Substance Name: Rilpivirine [USAN:INN]
RN: 500287-72-9
UNII: FI96A8X663
InChIKey: YIBOMRUWOWDFLG-ONEGZZNKSA-N
Note
- A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone.
Molecular Formula
- C22-H18-N6
Molecular Weight
- 366.4262
Classification Codes
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- Nucleic Acid Synthesis Inhibitors
- Reverse Transcriptase Inhibitors
- Treatment of HIV Infection
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Names and Synonyms
Name of Substance
- Rilpivirine
- Rilpivirine [USAN:INN]
MeSH Heading
- Rilpivirine
Synonyms
- 4-((4-((4-((1E)-2-Cyanoethenyl)-2,6-dimethylphenyl)amino)-2-pyrimidinyl)amino)benzonitrile
- Edurant
- HSDB 8153
- R 278474
- R278474
- Rilpivirine
- TMC 278
- TMC-278
- TMC278
- UNII-FI96A8X663
Systematic Name
- Benzonitrile, 4-((4-((4-((1E)-2-cyanoethenyl)-2,6-dimethylphenyl)amino)-2-pyrimidinyl)amino)-
Registry Numbers
CAS Registry Number
- 500287-72-9
FDA UNII
- FI96A8X663
System Generated Number
- 0500287729