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Substance Name: Meropenem [USAN:USP:INN:BAN]
RN: 119478-56-7
UNII: FV9J3JU8B1
InChIKey: CTUAQTBUVLKNDJ-OBZXMJSBSA-N

Note

  • A thienamycin derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of bacterial infections, including infections in immunocompromised patients.

Molecular Formula

  • C17-H25-N3-O5-S.3H2-O

Molecular Weight

  • 437.5109
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibacterial

Names and Synonyms

Name of Substance

  • Meropenem [USAN:USP:INN:BAN]

MeSH Heading

  • Meropenem

Synonyms

  • (4R,5S,6S)-3-(((3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, trihydrate
  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-((dimethylamino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, (4R-(3(3S*,5S*),4alpha,5beta,6beta(R*)))-
  • ICI 194,660
  • Meropenem
  • Meropenem trihydrate
  • Merrem
  • Merrem I.V.
  • NSC 759621
  • SM-7338
  • UNII-FV9J3JU8B1

Systematic Name

  • 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-((dimethylamino)carbonyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, trihydrate, (4R-(3(3S*,5S*),4alpha,5beta,6beta(R*)))-

Registry Numbers

CAS Registry Number

  • 119478-56-7

FDA UNII

  • FV9J3JU8B1

System Generated Number

  • 0119478567

Molecular Formulas

Molecular Formula

  • C17-H25-N3-O5-S.3H2-O

Molecular Formula Fragments

  • C17-H25-N3-O5-S
  • COMPONENT
  • H2-O

Structure Descriptors

InChI

InChI=1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1

InChIKey

CTUAQTBUVLKNDJ-OBZXMJSBSA-N

Smiles

O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(=C(N2C1=O)C(=O)O)S[C@@H]3CN[C@@H](C3)C(=O)N(C)C