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Substance Name: Lithium chloride
RN: 7447-41-8
UNII: G4962QA067
InChIKey: KWGKDLIKAYFUFQ-UHFFFAOYSA-M
Note
- A salt of lithium that has been used experimentally as an immunomodulator.
Molecular Formula
- Cl-Li
Molecular Weight
- 42.394
Classification Codes
- Adjuvants, Immunologic
- Antimanic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Drug / Therapeutic Agent
- Human Data
- Immunologic Factors
- Mutation Data
- Psychotropic Drugs
- Reproductive Effect
- Skin / Eye Irritant
- Tranquilizing Agents
- Tumor Data
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Names and Synonyms
Name of Substance
- Lithium chloride
MeSH Heading
- Lithium chloride
Synonyms
- CCRIS 5924
- Chlorku litu
- Chlorku litu [Polish]
- Chlorure de lithium
- Chlorure de lithium [French]
- EC 231-212-3
- EINECS 231-212-3
- HSDB 4281
- Lithium chloride
- NSC 327172
- UNII-G4962QA067
Systematic Names
- Lithium chloride
- Lithium chloride (LiCl)
Superlist Name
- Luthium chloride
Registry Numbers
CAS Registry Number
- 7447-41-8
FDA UNII
- G4962QA067
Other Registry Numbers
- 1220508-63-3
- 1309791-76-1
- 2018280-04-9
- 404596-80-1
System Generated Number
- 0007447418
Structure Descriptors
InChI
InChI=1S/ClH.Li/h1H;/q;+1/p-1InChIKey
KWGKDLIKAYFUFQ-UHFFFAOYSA-MSmiles
[Li]ClToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
bird - wild | LD50 | oral | 422mg/kg (422mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
cat | LD50 | intraperitoneal | 492mg/kg (492mg/kg) | Russian Pharmacology and Toxicology Vol. 42, Pg. 9, 1979. | |
cat | LDLo | subcutaneous | 450mg/kg (450mg/kg) | Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. | |
dog | LDLo | intravenous | 500mg/kg (500mg/kg) | GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS MUSCULOSKELETAL: OTHER CHANGES BEHAVIORAL: FOOD INTAKE (ANIMAL) | Journal of Pharmacology and Experimental Therapeutics. Vol. 100, Pg. 429, 1950. |
frog | LDLo | subcutaneous | 885mg/kg (885mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
guinea pig | LD50 | intraperitoneal | 624mg/kg (624mg/kg) | "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 157, 1999. | |
guinea pig | LDLo | subcutaneous | 620mg/kg (620mg/kg) | Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. | |
human | LDLo | oral | 200mg/kg/3D (200mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: MUSCLE WEAKNESS | JAMA, Journal of the American Medical Association. Vol. 139, Pg. 688, 1949. |
human | TDLo | oral | 243mg/kg/13D (243mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: TREMOR | JAMA, Journal of the American Medical Association. Vol. 139, Pg. 688, 1949. |
mouse | LD50 | intracrebral | 14040ug/kg (14.04mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 69, Pg. 75, 1973. |
mouse | LD50 | intraperitoneal | 600mg/kg (600mg/kg) | Journal of Thermal Biology. Vol. 6, Pg. 87, 1981. | |
mouse | LD50 | intravenous | 363mg/kg (363mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS | Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 413, 1973. |
mouse | LD50 | oral | 1165mg/kg (1165mg/kg) | Russian Pharmacology and Toxicology Vol. 33, Pg. 266, 1970. | |
mouse | LD50 | subcutaneous | 738mg/kg (738mg/kg) | MUSCULOSKELETAL: OTHER CHANGES BEHAVIORAL: TREMOR | Acta Pharmacologica et Toxicologica. Vol. 43, Pg. 51, 1978. |
pigeon | LDLo | subcutaneous | 513mg/kg (513mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
quail | LD50 | oral | 422mg/kg (422mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
rabbit | LD50 | oral | 800mg/kg (800mg/kg) | Farmakologiya i Toksikologiya Vol. 39, Pg. 53, 1976. | |
rabbit | LDLo | subcutaneous | 531mg/kg (531mg/kg) | Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. | |
rat | LD50 | intracrebral | 4800ug/kg (4.8mg/kg) | Polish Journal of Pharmacology and Pharmacy. Vol. 26, Pg. 399, 1974. | |
rat | LD50 | intracrebral | 4800ug/kg (4.8mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Polish Journal of Pharmacology and Pharmacy. Vol. 26, Pg. 399, 1974. |
rat | LD50 | intraperitoneal | 514mg/kg (514mg/kg) | Personal Communication from K.P. Petersen, DAK Labs., 59 Lergravsvej, DK-2300, Copenhagen, Demark, Dec. 22, 1977Vol. 22DEC1977, | |
rat | LD50 | intratracheal | 205mg/kg (205mg/kg) | "Spravochnik po Toksikologii i Gigienicheskim Normativam Vol. -, Pg. 157, 1999. | |
rat | LD50 | oral | 526mg/kg (526mg/kg) | Acta Pharmacologica et Toxicologica. Vol. 47, Pg. 351, 1980. | |
rat | LD50 | subcutaneous | 499mg/kg (499mg/kg) | Personal Communication from K.P. Petersen, DAK Labs., 59 Lergravsvej, DK-2300, Copenhagen, Demark, Dec. 22, 1977Vol. 22DEC1977, |