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Substance Name: Glutathione [BAN:JAN]
RN: 70-18-8
UNII: GAN16C9B8O
InChIKey: RWSXRVCMGQZWBV-WDSKDSINSA-N
Note
- A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
Molecular Formula
- C10-H17-N3-O6-S
Molecular Weight
- 307.3253
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Antiviral (COVID-19)
- Mutation Data
- Reproductive Effect
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Names and Synonyms
Name of Substance
- Glutathione
- Glutathione [BAN:JAN]
- Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-
- N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine
MeSH Heading
- Glutathione
Synonyms
- CCRIS 2094
- Copren
- Deltathione
- EINECS 200-725-4
- gamma-L-Glutamyl-L-cysteinylglycine
- gamma-L-Glutamylcysteinylglycine
- Glutathion
- Glutathione
- Glutathione (reduced)
- Glutathione SH
- Glutathione-SH
- Glutatiol
- Glutatione
- Glutide
- Glutinal
- GSH
- Isethion
- L-Glutathione
- L-Glutatione
- Ledac
- Neuthion
- NSC 400639
- Panaron
- Reduced glutathione
- Tathion
- Tathione
- Triptide
- UNII-GAN16C9B8O
Systematic Names
- Glutathione
- Glycine, L-gamma-glutamyl-L-cysteinyl-
- Glycine, N-(N-L-gamma-glutamyl-L-cysteinyl)-
- N-(N-L-gamma-Glutamyl-L-cysteinyl)glycine
Registry Numbers
CAS Registry Number
- 70-18-8
FDA UNII
- GAN16C9B8O
Other Registry Numbers
- 1109226-07-4
- 1655518-50-5
System Generated Number
- 0000070188
Structure Descriptors
InChI
InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1InChIKey
RWSXRVCMGQZWBV-WDSKDSINSA-NSmiles
N[C@@H](CCC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intramuscular | 4gm/kg (4000mg/kg) | "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Suppl Exporters' Assoc., 1968Vol. -, Pg. 97, 1968. | |
mouse | LD50 | intraperitoneal | 4020mg/kg (4020mg/kg) | "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972. | |
mouse | LD50 | intravenous | 2238mg/kg (2238mg/kg) | Japanese Journal of Antibiotics. Vol. 38, Pg. 137, 1985. | |
mouse | LD50 | oral | 5gm/kg (5000mg/kg) | "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972. | |
mouse | LD50 | subcutaneous | 5gm/kg (5000mg/kg) | "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972. | |
rabbit | LD50 | intravenous | > 2gm/kg (2000mg/kg) | Biochemical Journal. Vol. 41, Pg. 325, 1947. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 195 | deg C | EXP | |
log P (octanol-water) | -5.410 | (none) | EST | |
Atmospheric OH Rate Constant | 1.26E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.