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Substance Name: Inamrinone lactate
RN: 75898-90-7
UNII: I229274Y5B
InChIKey: DOSIONJFGDSKCQ-UHFFFAOYSA-N

Note

  • A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.

Molecular Formula

  • C10-H9-N3-O.x-C3-H6-O3

Molecular Weight

  • 277.2785
 

Classification Codes

  • Drug / Therapeutic Agent
  • Human Data
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Names and Synonyms

Results Name

  • Inamrinone lactate

Name of Substance

  • Inamrinone lactate

Synonyms

  • 3-Hydroxypropanoic acid compd. with 5-amino-(3,4'-bipyridin)-6(1H)-one
  • Amrinone
  • Amrinone lactate
  • Inamrinone lactate
  • Inocor
  • UNII-I229274Y5B

Systematic Names

  • (3,4'-Bipyridin)-6(1H)-one, 5-amino-, 3-hydroxypropanoate
  • Propanoic acid, 3-hydroxy-, compd. with 5-amino-(3,4'-bipyridin)-6(1H)-one

Registry Numbers

CAS Registry Number

  • 75898-90-7

FDA UNII

  • I229274Y5B

System Generated Number

  • 0075898907

Molecular Formulas

Molecular Formula

  • C10-H9-N3-O.x-C3-H6-O3

Molecular Formula Fragments

  • C10-H9-N3-O
  • C3-H6-O3
  • COMPONENT

Structure Descriptors

InChI

1S/C10H9N3O.C3H6O3/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7;1-2(4)3(5)6/h1-6H,11H2,(H,13,14);2,4H,1H3,(H,5,6)

InChIKey

DOSIONJFGDSKCQ-UHFFFAOYSA-N

Smiles

CC(C(=O)O)O.c1cnccc1c2cc(c(=O)[nH]c2)N

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man LDLo intravenous 26mg/kg/6D-I (26mg/kg) CARDIAC: OTHER CHANGES

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)
South African Medical Journal. Vol. 66, Pg. 6, 1984.