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Substance Name: Celecoxib [USAN:INN:BAN]
RN: 169590-42-5
UNII: JCX84Q7J1L
InChIKey: RZEKVGVHFLEQIL-UHFFFAOYSA-N
Note
- A pyrazole derivative and selective CYCLOOXYGENASE 2 INHIBITOR that is used to treat symptoms associated with RHEUMATOID ARTHRITIS; OSTEOARTHRITIS and JUVENILE ARTHRITIS, as well as the management of ACUTE PAIN.
Molecular Formula
- C17-H14-F3-N3-O2-S
Molecular Weight
- 381.3766
- All
- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Physical Properties
Classification Codes
- Analgesic
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Anti-Inflammatory and Analgesic (Cyclooxygenase-2 Inhibitor)
- Antirheumatic Agents
- Cyclooxygenase 2 Inhibitors
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
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Names and Synonyms
Name of Substance
- Celecoxib
- Celecoxib [USAN:INN:BAN]
MeSH Heading
- Celecoxib
Synonyms
- 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
- CCRIS 9330
- Celebra
- Celebrex
- Celecoxib
- HSDB 7038
- Onsenal
- p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
- SC 58635
- SC-58635
- UNII-JCX84Q7J1L
- Xilebao
- YM 177
- YM177
Systematic Name
- Benzenesulfonamide, 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)-
Registry Numbers
CAS Registry Number
- 169590-42-5
FDA UNII
- JCX84Q7J1L
Other Registry Numbers
- 184007-95-2
- 194044-54-7
System Generated Number
- 0169590425
Structure Descriptors
InChI
InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)InChIKey
RZEKVGVHFLEQIL-UHFFFAOYSA-NSmiles
Cc1ccc(cc1)Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 158 | deg C | EXP | |
log P (octanol-water) | 3.470 | (none) | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.