Skip Navigation
ChemIDplus Lite•Browse•Advanced

Substance Name: Indigotindisulfonate sodium [USP]
RN: 860-22-0
InChIKey: KHLVKKOJDHCJMG-QDBORUFSSA-L

Note

  • Indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk.

Molecular Formulas

  • C16-H10-N2-O8-S2.2Na
  • C16-H8-N2-Na2-O8-S2
  • C16-H8-N2-O8-S2.2Na

Molecular Weight

  • 466.3572
 

Classification Codes

  • Coloring Agents
  • Diagnostic Aid (Cystoscopy)
  • Drug / Therapeutic Agent
  • Mutation Data
  • Tumor Data
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Regulatory Agencies (Superlist Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • 1H-Indole-5-sulfonic acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, disodium salt
  • CI 73015
  • Indigo carmine
  • Indigotindisulfonate sodium
  • Indigotindisulfonate sodium [USP]

MeSH Heading

  • Indigo carmine

Synonyms

  • (delta2,2'-Biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt
  • 12070 Blue
  • 1311 Blue
  • 1H-Indole-5-sulfonic acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, disodium salt
  • 2-(1,3-Dihydro-3-oxo-5-sulfo-2h-indol-2-ylidene)-2,3-dihydro-3-oxo-1h-indole-5-sulfonic acid disodium salt
  • 2-(1,3-Dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-1H-indole-5-sulfonic acid, disodium salt
  • 3,3'-Dioxo-(delta2,2'-biindoline)-5,5'-disulfonic acid disodium salt
  • 5,5'-Indigotin disulfonic acid
  • A.F. Blue No. 2
  • Acid Blue 74
  • Acid Blue W
  • Acid Leather Blue IC
  • AF blue no. 2
  • AI3-09087
  • Airdale blue IN
  • Airedale Blue IN
  • Amacid Brilliant Blue
  • Aniline Carmine powder
  • Atul Indigo Carmine
  • Bucacid indigotine B
  • C.I. 73015
  • C.I. 75781
  • C.I. Acid Blue 74
  • C.I. Food Blue 1
  • C.I. Food Blue 1, disodium salt
  • C.I. Natural Blue 2
  • Canacert Indigo Carmine
  • Carmine Blue (biological stain)
  • CCRIS 1865
  • CI 73015
  • Cilefa Blue R
  • Dinatrium 3,3'-dioxo-(delta2,2'-biindolin)-5,5'-disulfonat
  • Dinatrium indigolin-5,5'-disulfonat
  • Disodium 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-1H-indole-5-sulfonate
  • Disodium 3,3'-dioxo-(delta(sup 2,2')-biindoline)-5,5'-disulfonate
  • Disodium 3,3'-dioxo-(delta2,2'-biindoline)-5,5'-disulfonate
  • Disodium 5,5'-disulfoindigo
  • Disodium 5,5'-indigotin disulfonate
  • Disodium indigo-5,5-disulfonate
  • Disodium salt of 1-indigotin-S,S'-disulfonic acid
  • Disodium salt of 1-indigotin-S,S'-disulphonic acid
  • Dolkwal Indigo Carmine
  • E 132
  • Edicol Supra Blue X
  • EINECS 212-728-8
  • FD &C Blue No. 2
  • FD and C Blue No. 2
  • FD&C blue no. 2
  • Food Blue 1
  • Food Blue 2
  • Food Blue No. 1
  • Food Blue No. 2
  • Grape Blue A
  • Grape Blue A Geigy
  • HD Indigo Carmine
  • HD Indigo Carmine Supra
  • Hexacert Blue No. 2
  • Hexacol Indigo Carmine Supra
  • HSDB 7875
  • Indigo carmine
  • Indigo Carmine (biological stain)
  • Indigo Carmine A
  • Indigo Carmine AC
  • Indigo Carmine BP
  • Indigo Carmine Conc. FQ
  • Indigo Carmine disodium salt
  • Indigo Carmine powder
  • Indigo Carmine X
  • Indigo disulfonate (biological stain)
  • Indigo extract
  • Indigo-karmin
  • Indigo-karmin [German]
  • Indigocarmin
  • Indigocarmine
  • Indigotin I
  • Indigotin-5,5'-disulfonic acid disodium salt
  • Indigotindisulfonate sodium
  • Indigotine
  • Indigotine B
  • Indigotine Blue LZ
  • Indigotine conc. powder
  • Indigotine Conc. Powder; Indigotine Extra Pure A
  • Indigotine disodium salt
  • Indigotine Extra Pure A
  • Indigotine I
  • Indigotine IA
  • Indigotine Lake
  • Indigotine N
  • Indocarmine F
  • Intense Blue
  • L Blue Z 5010
  • L-Blau 2
  • L-Blau 2 [German]
  • Maple Indigo Carmine
  • Mitsui Indigo Carmine
  • Modr Kysela 74
  • Modr Kysela 74 [Czech]
  • Modr Pigment 63
  • Modr Pigment 63 [Czech]
  • Modr Potravinarska 1
  • Modr Potravinarska 1 [Czech]
  • Murabba
  • NSC 8646
  • Sachsischblau
  • San-ei Indigo Carmine
  • Schultz Nr. 1309
  • Schultz Nr. 1309 [German]
  • Sodium 5,5'-indigotindisulfonate
  • Sodium indigo-5,5'-bisulfonate
  • Sodium indigotin disulfonate
  • Sodium indigotindisulfonate
  • Soluble indigo
  • Soluble indigo blue
  • Sumitomo Wool Blue SBC
  • UNII-D3741U8K7L
  • UNII-L06K8R7DQK
  • Usacert Blue No. 2

Systematic Names

  • (delta(sup 2,2')-Biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt
  • (delta2,2'-Biindoline)-5,5'-disulfonic acid, 3,3'-dioxo-, disodium salt
  • 1H-Indole-5-sulfonic acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, disodium salt
  • 1H-Indole-5-sulfonic acid, 2-(1,3-dihydro-3-oxo-5-sulfo-2H-indol-2-ylidene)-2,3-dihydro-3-oxo-, sodium salt (1:2)
  • Disodium 5,5'-(2-(1,3-dihydro-3-oxo-2H-indazol-2-ylidene)-1,2-dihydro-3H-indol-3-one)disulphonate
  • FD&C Blue No. 2

Superlist Name

  • FD&C Blue No. 2

Registry Numbers

CAS Registry Number

  • 860-22-0

FDA UNIIs

  • D3741U8K7L
  • L06K8R7DQK

System Generated Number

  • 0000860220

Molecular Formulas

Molecular Formulas

  • C16-H10-N2-O8-S2.2Na
  • C16-H8-N2-Na2-O8-S2
  • C16-H8-N2-O8-S2.2Na

Molecular Formula Fragments

  • C16-H10-N2-O8-S2
  • C16-H8-N2-O8-S2
  • COMPONENT
  • Na

Structure Descriptors

InChI

InChI=1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;

InChIKey

KHLVKKOJDHCJMG-QDBORUFSSA-L

Smiles

[Na+].[Na+].[O-]S(=O)(=O)c1ccc2N\C(=C/3\Nc4ccc(cc4C3=O)S(=O)(=O)[O-])\C(=O)c2c1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 2500mg/kg (2500mg/kg)   Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.
mouse LD50 subcutaneous 405mg/kg (405mg/kg)   Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.
rat LD50 intravenous 93mg/kg (93mg/kg)   Drugs in Japan Vol. 6, Pg. 83, 1982.
rat LD50 oral 2gm/kg (2000mg/kg)   Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) -3.570 (none)   EST
Water Solubility 1.00E+04 mg/L 25 EXP
Atmospheric OH Rate Constant 2.15E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.