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Substance Name: (+-)-Terbutaline
RN: 23031-25-6
UNII: N8ONU3L3PG
InChIKey: XWTYSIMOBUGWOL-UHFFFAOYSA-N

Note

  • A selective beta-2 adrenergic agonist used as a bronchodilator and tocolytic.

Molecular Formula

  • C12-H19-N-O3

Molecular Weight

  • 225.2861
 

Classification Codes

  • Adrenergic Agents
  • Adrenergic Agonists
  • Adrenergic beta-2 Receptor Agonists
  • Adrenergic beta-Agonists
  • Anti-Asthmatic Agents
  • Autonomic Agents
  • Bronchodilator Agents
  • Drug / Therapeutic Agent
  • Human Data
  • Neurotransmitter Agents
  • Peripheral Nervous System Agents
  • Reproductive Control Agents
  • Reproductive Effect
  • Respiratory System Agents
  • Sympathomimetics
  • Tocolytic Agents

Names and Synonyms

Results Name

  • (+-)-Terbutaline

Name of Substance

  • Terbutaline
  • Terbutaline [INN:BAN]

MeSH Heading

  • Terbutaline

Synonyms

  • (+-)-5-(2-((1,1-Dimethylethyl)amino)-1-hydroxyethyl)-1,3-benzenediol
  • (+-)-Terbutaline
  • 5-(2-((1,1-Dimethylethyl)amino)-1-hydroxyethyl)-1,3-benzenediol
  • Brican
  • Bricar
  • Bricaril
  • Bricyn
  • BRN 2370513
  • EINECS 245-385-8
  • KWD 2019
  • Terbutalin
  • Terbutalina
  • Terbutalina [DCIT]
  • Terbutaline
  • Terbutalino
  • Terbutalino [INN-Spanish]
  • Terbutalinum
  • Terbutalinum [INN-Latin]
  • UNII-N8ONU3L3PG

Systematic Names

  • 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-
  • 1,3-Benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-, (+-)-
  • Benzyl alcohol, alpha-((t-butylamino)methyl)-3,5-dihydroxy-
  • Terbutaline

Registry Numbers

CAS Registry Number

  • 23031-25-6

FDA UNII

  • N8ONU3L3PG

Other Registry Number

  • 46719-29-3

Related Registry Number

  • 23031-32-5 (Sulfate)

System Generated Number

  • 0023031256

Structure Descriptors

InChI

InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8/h4-6,11,13-16H,7H2,1-3H3

InChIKey

XWTYSIMOBUGWOL-UHFFFAOYSA-N

Smiles

CC(C)(C)NCC(O)c1cc(O)cc(O)c1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 714ug/kg (0.714mg/kg) BEHAVIORAL: TREMOR

CARDIAC: CHANGE IN RATE

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)		 New England Journal of Medicine. Vol. 300, Pg. 143, 1979.
women TDLo multiple routes 380ug/kg (0.38mg/kg) CARDIAC: OTHER CHANGES JAMA, Journal of the American Medical Association. Vol. 244, Pg. 692, 1980.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 0.9 (none)   EXP
Water Solubility 2.13E+05 mg/L 25 EST
Vapor Pressure 1.00E-07 mm Hg 25 EST
Henry's Law Constant 1.65E-18 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 2.83E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.