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Substance Name: Poziotinib [INN]
RN: 1092364-38-9
UNII: OEI6OOU6IK
InChIKey: LPFWVDIFUFFKJU-UHFFFAOYSA-N

Note

  • Antitumor irreversible Pan-HER inhibitor for treatment of gastric cancer.

Classification Code

  • Antineoplastic

Molecular Formula

  • C23-H21-Cl2-F-N4-O3

Molecular Weight

  • 491.3479
 
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Names and Synonyms

Results Name

  • Poziotinib [INN]

Name of Substance

  • Poziotinib
  • Poziotinib [INN]
  • Poziotinib [USAN]

Synonyms

  • HM-781-36
  • HM-781-36B
  • NOV-1201
  • NOV-120101
  • Poziotinib
  • UNII-OEI6OOU6IK
  • WHO 9736

Registry Numbers

CAS Registry Number

  • 1092364-38-9

FDA UNII

  • OEI6OOU6IK

Other Registry Number

  • 1346176-39-3

System Generated Number

  • 1092364389

Structure Descriptors

InChI

InChI=1S/C23H21Cl2FN4O3/c1-3-20(31)30-8-6-13(7-9-30)33-19-10-14-17(11-18(19)32-2)27-12-28-23(14)29-16-5-4-15(24)21(25)22(16)26/h3-5,10-13H,1,6-9H2,2H3,(H,27,28,29)

InChIKey

LPFWVDIFUFFKJU-UHFFFAOYSA-N

Smiles

COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC4CCN(CC4)C(=O)C=C