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Substance Name: Risedronate sodium [USAN:USP]
RN: 115436-72-1
UNII: OFG5EXG60L
InChIKey: DRFDPXKCEWYIAW-UHFFFAOYSA-M

Note

  • An aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatment of OSTEOPOROSIS.

Molecular Formula

  • C7-H10-N-O7-P2.Na

Molecular Weight

  • 305.094
 

Classification Codes

  • Bone Density Conservation Agents
  • Calcium Channel Blockers
  • Cardiovascular Agents
  • Drug / Therapeutic Agent
  • Human Data
  • Membrane Transport Modulators
  • Regulator (Calcium)
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Names and Synonyms

Name of Substance

  • Risedronate sodium [USAN:USP]

MeSH Heading

  • Risedronate Sodium

Synonyms

  • Actonel
  • Atelvia
  • Monosodium (1-hydroxy-2-(3-pyridinyl)ethylidene)bisphosphonate
  • NE 58095
  • NE-58095
  • NSC 722598
  • NSC 759280
  • Risedronate sodium
  • Sodium risedronate
  • Sodium trihydrogen (1-hydroxy-2-(3-pyridyl)ethylidene)diphosphonate
  • UNII-OFG5EXG60L

Systematic Name

  • Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-, monosodium salt

Registry Numbers

CAS Registry Number

  • 115436-72-1

FDA UNII

  • OFG5EXG60L

Related Registry Number

  • 105462-24-6 (Parent)

System Generated Number

  • 0115436721

Molecular Formulas

Molecular Formula

  • C7-H10-N-O7-P2.Na

Molecular Formula Fragments

  • C7-H10-N-O7-P2
  • COMPONENT
  • Na

Structure Descriptors

InChI

InChI=1S/C7H11NO7P2.Na/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);/q;+1/p-1

InChIKey

DRFDPXKCEWYIAW-UHFFFAOYSA-M

Smiles

[Na+].OC(Cc1cccnc1)(P(=O)(O)O)P(=O)(O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 1800ug/kg/3D- (1.8mg/kg) SENSE ORGANS AND SPECIAL SENSES: IRITIS: EYE Lancet. Vol. 341, Pg. 436, 1993.