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Substance Name: Etanercept [USAN:INN:BAN]
RN: 185243-69-0
UNII: OP401G7OJC
Note
- A recombinant version of soluble human TNF receptor that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS.
Molecular Formulas
- C2224-H3472-N618-O701-S36
- Unspecified
Molecular Weight
- 51166.8153
Classification Codes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Gastrointestinal Agents
- Immunologic Factors
- Immunosuppressive Agents
- Peripheral Nervous System Agents
- Sensory System Agents
- To Decrease Signs and Symptoms of Rheumatoid Arthritis
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Etanercept [USAN:INN:BAN]
- Etanercept-szzs
- TNFR-Fc fusion protein
MeSH Heading
- Etanercept
Synonyms
- 1-235-Tumor necrosis factor receptor (human) fusion protein with 236-467-immunoglobulin G1 (human gamma1-chain Fc fragment), dimer
- Enbrel
- Erelzi
- Etanercept
- Etanercept-szzs [Biosimilar]
- HSDB 7849
- Recombinant human dimeric TNF receptor type II-IgG fusion protein
- Recombinant human TNF
- rhu TNFR:Fc
- TNF receptor type II-IgG fusion protein
- TNFR-Fc
- TNFR:Fc
- TNR 001
- UNII-OP401G7OJC
Systematic Name
- 1-235-Tumor necrosis factor receptor (human) fusion protein with 236-467-immunoglobulin G1 (human gamma1-chain Fc fragment)
Registry Numbers
CAS Registry Number
- 185243-69-0
FDA UNII
- OP401G7OJC
Other Registry Number
- 200013-86-1
System Generated Number
- 0185243690