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Substance Name: Tenofovir Disoproxil Fumarate [USAN]
RN: 202138-50-9
UNII: OTT9J7900I
InChIKey: VCMJCVGFSROFHV-WZGZYPNHSA-N

Classification Codes

  • Antiviral
  • Antiviral (COVID-19)
  • Antiviral (Reverse Transcriptase Inhibitor)

Molecular Formula

  • C19-H30-N5-O10-P.C4-H4-O4

Molecular Weight

  • 635.5166
 

Names and Synonyms

Name of Substance

  • Tenofovir Disoproxil Fumarate [USAN]

Synonyms

  • (R)-5-((2-(6-Amino-9H-purin-9-yl)-1-methylethoxy)methyl)-2,4,6,8-tetraoxa-5-phosphanonanedioic acid, bis(1-methylethyl) ester, 5-oxide, (E)-2-butenedioate (1:1)
  • 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarate (1:1)
  • Bis(hydroxymethyl) (((R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy)methyl)phosphonate, bis(isopropyl carbonate) (ester), fumarate (1:1)
  • GS 4331-05
  • GS-4331-05
  • HSDB 7165
  • PMPA prodrug
  • TDF
  • Tenofovir DF
  • Tenofovir disoproxil fumarate
  • UNII-OTT9J7900I
  • Viread

Systematic Name

  • 9-((R)-2-((Bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine, fumarate

Mixture Name

  • Truvada

Registry Numbers

CAS Registry Number

  • 202138-50-9

FDA UNII

  • OTT9J7900I

System Generated Number

  • 0202138509

Molecular Formulas

Molecular Formula

  • C19-H30-N5-O10-P.C4-H4-O4

Molecular Formula Fragments

  • C19-H30-N5-O10-P
  • C4-H4-O4
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C19H30N5O10P.C4H4O4/c1-12(2)33-18(25)28-9-31-35(27,32-10-29-19(26)34-13(3)4)11-30-14(5)6-24-8-23-15-16(20)21-7-22-17(15)24;5-3(6)1-2-4(7)8/h7-8,12-14H,6,9-11H2,1-5H3,(H2,20,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1+/t14-;/m1./s1

InChIKey

VCMJCVGFSROFHV-WZGZYPNHSA-N

Smiles

CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc12)OCOC(=O)OC(C)C.OC(=O)\C=C\C(=O)O