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Substance Name: Prochlorperazine edisylate [USP]
RN: 1257-78-9
UNII: PG20W5VQZS
InChIKey: SWOUGRBFXFILIB-UHFFFAOYSA-N

Classification Codes

  • Anti-Emetic
  • Antipsychotic
  • Reproductive Effect

Molecular Formula

  • C20-H24-Cl-N3-S.C2-H6-O6-S2

Molecular Weight

  • 564.145
 
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Names and Synonyms

Name of Substance

  • Prochlorperazine edisylate
  • Prochlorperazine edisylate [USP]

Synonyms

  • 10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-, 1,2-ethanedisulfonate (1:1)
  • 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine edisylate
  • 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine 1,2-ethanedisulfonate (1:1)
  • Compazine
  • Compazine Injection
  • Compazine syrup
  • EINECS 215-019-1
  • Prochlorperazine edisylate
  • Prochlorperazine ethane disulfonate
  • Stemetil
  • UNII-PG20W5VQZS

Systematic Names

  • 1,2-Ethanedisulfonic acid, compd. with 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazine (1:1)
  • 10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-, 1,2-ethanedisulfonate (1:1)
  • Ethane-1,2-disulphonic acid, compound with 2-chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine (1:1)
  • Phenothiazine, 2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-, ethanedisulfonate

Registry Numbers

CAS Registry Number

  • 1257-78-9

FDA UNII

  • PG20W5VQZS

Other Registry Number

  • 7081-50-7

System Generated Number

  • 0001257789

Molecular Formulas

Molecular Formula

  • C20-H24-Cl-N3-S.C2-H6-O6-S2

Molecular Formula Fragments

  • C2-H6-O6-S2
  • C20-H24-Cl-N3-S
  • COMPONENT

Structure Descriptors

InChI

InChI=1S/C20H24ClN3S.C2H6O6S2/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;3-9(4,5)1-2-10(6,7)8/h2-3,5-8,15H,4,9-14H2,1H3;1-2H2,(H,3,4,5)(H,6,7,8)

InChIKey

SWOUGRBFXFILIB-UHFFFAOYSA-N

Smiles

CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1.OS(=O)(=O)CCS(=O)(=O)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 177mg/kg (177mg/kg)   Psychopharmacologia Vol. 12, Pg. 142, 1968.
mouse LD50 oral 400mg/kg (400mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 40, 1972.
mouse LD50 subcutaneous 320mg/kg (320mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 40, 1972.