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Substance Name: Tivantinib [USAN:INN]
RN: 905854-02-6
UNII: PJ4H73IL17
InChIKey: UCEQXRCJXIVODC-PMACEKPBSA-N

Note

  • An oral small-molecule inhibitor of c-Met for the treatment of solid tumors.

Classification Code

  • Antineoplastic

Molecular Formula

  • C23-H19-N3-O2

Molecular Weight

  • 369.4221
 
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Names and Synonyms

Name of Substance

  • Tivantinib [USAN:INN]

Synonyms

  • (3R,4R)-3-(5,6-Dihydro-4H-pyrrolo(3,2,1-ij)quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione
  • ARQ 197
  • Tivantinib
  • UNII-PJ4H73IL17

Systematic Name

  • 2,5-Pyrrolidinedione, 3-(5,6-dihydro-4H-pyrrolo(3,2,1-ij)quinolin-1-yl)-4-(1H-indol-3-yl)-, (3R,4R)-

Registry Numbers

CAS Registry Number

  • 905854-02-6

FDA UNII

  • PJ4H73IL17

Other Registry Numbers

  • 1000873-98-2
  • 1228508-24-4

System Generated Number

  • 0905854026

Structure Descriptors

InChI

InChI=1S/C23H19N3O2/c27-22-19(16-11-24-18-9-2-1-7-14(16)18)20(23(28)25-22)17-12-26-10-4-6-13-5-3-8-15(17)21(13)26/h1-3,5,7-9,11-12,19-20,24H,4,6,10H2,(H,25,27,28)/t19-,20-/m0/s1

InChIKey

UCEQXRCJXIVODC-PMACEKPBSA-N

Smiles

O=C1NC(=O)[C@H]([C@@H]1c2c[nH]c3ccccc23)c4cn5CCCc6cccc4c56