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Substance Name: Fosinopril [INN:BAN]
RN: 98048-97-6
UNII: R43D2573WO
InChIKey: BIDNLKIUORFRQP-FLODCBCLSA-N
Note
- A phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.
Molecular Formula
- C30-H46-N-O7-P
Molecular Weight
- 563.6625
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- Classifications
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- Registry Numbers
- Structure Descriptors
- Physical Properties
Classification Codes
- Angiotensin-Converting Enzyme Inhibitors
- Antihypertensive Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Protease Inhibitors
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Names and Synonyms
Name of Substance
- Fosinopril
- Fosinopril [INN:BAN]
MeSH Heading
- Fosinopril
Synonyms
- Fosinopril
- UNII-R43D2573WO
Systematic Names
- L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, (1(S*(R*)),2alpha,4beta)-
- L-Proline, 4-cyclohexyl-1-(((2-methyl-1-(1-oxopropoxy)propoxy)(4-phenylbutyl)phosphinyl)acetyl)-, (2alpha,4beta)-
Registry Numbers
CAS Registry Number
- 98048-97-6
FDA UNII
- R43D2573WO
System Generated Number
- 0098048976
Structure Descriptors
InChI
1S/C30H46NO7P/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)/t25-,26+,30+,39+/m1/s1InChIKey
BIDNLKIUORFRQP-FLODCBCLSA-NSmiles
CCC(=O)Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | 6.610 | (none) | EST | |
Atmospheric OH Rate Constant | 1.29E-10 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.