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Substance Name: Tridolgosir [INN]
RN: 72741-87-8
UNII: RSY4RK37KQ
InChIKey: FXUAIOOAOAVCGD-WCTZXXKLSA-N

Note

  • An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.

Molecular Formula

  • C8-H15-N-O3

Molecular Weight

  • 173.2105
 

Classification Codes

  • Adjuvants, Immunologic
  • Antineoplastic Agents
  • Antineoplastic Agents, Phytogenic
  • Enzyme Inhibitors
  • Immunologic Factors
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Names and Synonyms

Name of Substance

  • Swainsonine
  • Tridolgosir [INN]

MeSH Heading

  • Swainsonine

Synonyms

  • Swainsonine
  • Tridolgosir
  • UNII-RSY4RK37KQ

Systematic Name

  • 1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-

Registry Numbers

CAS Registry Number

  • 72741-87-8

FDA UNII

  • RSY4RK37KQ

System Generated Number

  • 0072741878

Structure Descriptors

InChI

InChI=1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7-,8-/m1/s1

InChIKey

FXUAIOOAOAVCGD-WCTZXXKLSA-N

Smiles

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