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Substance Name: Desmoteplase [USAN:INN]
RN: 145137-38-8
UNII: T36L245S3T


  • Displays strict fibrin specificity; cleared fourfold slower from circulation than t-PA.

Classification Codes

  • Cardiovascular Agents
  • Fibrinolytic Agents
  • Hematologic Agents
  • Treatment of Acute Myocardial Infarction, Acute Ischemic Stroke, Pulmonary Embolism and Hemodialysis
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Links to Resources

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Names and Synonyms

Name of Substance

  • Desmoteplase [USAN:INN]
  • Salivary plasminogen activator alpha 1, Desmodus rotundus


  • Desmoteplase
  • Plasminogen activator (Desmodus rotundus isoform alpha1 protein moiety reduced). Molecular weight is 55,000-58,000 daltons
  • rDSPA alpha 1
  • UNII-T36L245S3T

Registry Numbers

CAS Registry Number

  • 145137-38-8


  • T36L245S3T

System Generated Number

  • 0145137388