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Substance Name: Lofexidine [INN:BAN]
RN: 31036-80-3
UNII: UI82K0T627
InChIKey: KSMAGQUYOIHWFS-UHFFFAOYSA-N
Note
- Reduces narcotic withdrawal symptoms.
Molecular Formula
- C11-H12-Cl2-N2-O
Molecular Weight
- 259.1348
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Physical Properties
Classification Codes
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic alpha-2 Receptor Agonists
- Adrenergic alpha-Agonists
- Antihypertensive Agents
- Cardiovascular Agents
- Central Nervous System Agents
- Drug / Therapeutic Agent
- Narcotic Antagonists
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Reproductive Effect
- Sensory System Agents
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Links to Resources
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Names and Synonyms
Name of Substance
- Lofexidine
- Lofexidine [INN:BAN]
Synonyms
- 2-(1-(2,6-Dichlorophenoxy)ethyl)-4,5-dihydro-1H-imidazole
- 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline
- Lofexidina
- Lofexidina [INN-Spanish]
- Lofexidine
- Lofexidinum
- Lofexidinum [INN-Latin]
- UNII-UI82K0T627
Systematic Names
- 1H-Imidazole, 2-(1-(2,6-dichlorophenoxy)ethyl)-4,5-dihydro- (9CI)
- 2-Imidazoline 2-(1-(2,6-dichlorophenoxy)ethyl)-
Registry Numbers
CAS Registry Number
- 31036-80-3
FDA UNII
- UI82K0T627
Related Registry Number
- 21498-08-8 (mono-hydrochloride)
System Generated Number
- 0031036803
Structure Descriptors
InChI
InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)InChIKey
KSMAGQUYOIHWFS-UHFFFAOYSA-NSmiles
CC(Oc1c(Cl)Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
Melting Point | 127 | deg C | EXP | |
log P (octanol-water) | 3.580 | (none) | EST | |
Atmospheric OH Rate Constant | 8.71E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.