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Substance Name: Diazinon [ANSI:BSI:ISO]
RN: 333-41-5
UNII: YUS1M1Q929
InChIKey: FHIVAFMUCKRCQO-UHFFFAOYSA-N

Note

  • A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.

Molecular Formula

  • C12-H21-N2-O3-P-S

Molecular Weight

  • 304.3489
 

Classification Codes

Classification Codes

  • Acaricide
  • Agricultural Chemical
  • Cholinergic Agents
  • Cholinesterase Inhibitors
  • Enzyme Inhibitors
  • Human Data
  • Insecticide
  • Insecticides
  • Mutation Data
  • Nematocide
  • Neurotransmitter Agents
  • Pesticides
  • Reproductive Effect
  • Skin / Eye Irritant
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 56
  • 2011 CERCLA Priority List, Rank: 41
  • Overall Carcinogenic Evaluation: Group 2A
  • Reportable Quantity (RQ) = 1 lb
  • TWA 0.01 mg/m3 inhalable fraction vapor and aerosol; skin; Not classifiable as a human carcinogen; BEI

Names and Synonyms

Results Name

  • Diazinon [ANSI:BSI:ISO]

Name of Substance

  • Diazinon
  • Diazinon [ANSI:BSI:ISO]
  • Dimpylate [INN:BAN]

MeSH Heading

  • Diazinon

Synonyms

  • 4-Pyrimidinol, 2-isopropyl-6-methyl-, O-ester with O,O-diethyl phosphorothioate
  • 5-23-11-00187 (Beilstein Handbook Reference)
  • AG-500
  • AI3-19507
  • Alfa-Tox
  • Antigal
  • Bassadinon
  • Basudin
  • Basudin 10 G
  • Basudin S
  • Bazuden
  • BRN 0273790
  • Caswell No. 342
  • CCRIS 204
  • Ciazinon
  • Compass
  • Compass (insecticide)
  • Cooper's Flystrike Powder
  • Dacutox
  • Dassitox
  • Dazzel
  • Delzinon
  • Diazajet
  • Diazide
  • Diazinon
  • Diazinon ag 500
  • Diazinone
  • Diazitol
  • Diazol
  • Dicid
  • Diethyl 2-isopropyl-4-methyl-6-pyrimidinyl phosphorothionate
  • Diethyl 4-(2-isopropyl-6-methylpyrimidinyl)phosphorothionate
  • Dimpilato
  • Dimpilato [INN-Spanish]
  • Dimpylat
  • Dimpylate
  • Dimpylatum
  • Dimpylatum [INN-Latin]
  • Disonex
  • Dizictol
  • Dizinil
  • Dizinon
  • Drawizon
  • Dyzol
  • EINECS 206-373-8
  • Ektoband
  • ENT 19,507
  • EPA Pesticide Chemical Code 057801
  • Exodin
  • Flytrol
  • G 24480
  • G 301
  • G-24480
  • Galesan
  • Garden Tox
  • Geigy 24480
  • HSDB 303
  • Isopropylmethylpyrimidyl diethyl thiophosphate
  • Kayazinon
  • Kayazol
  • KFM Blowfly Dressing
  • Kleen-Dok
  • Knox Out 2FM
  • Knox Out Yellow Jacket Contorl
  • Knox-out
  • Meodinon
  • NCI-C08673
  • Nedcidol
  • Neocidol
  • Neocidol (oil)
  • Neodinon
  • Nipsan
  • NSC 8938
  • Nucidol
  • O,O-Diaethyl-O-(2-isopropyl-4-methyl)-6-pyrimidyl-thionophosphat
  • O,O-Diaethyl-O-(2-isopropyl-4-methyl)-6-pyrimidyl-thionophosphat [German]
  • O,O-Diaethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiophosphat
  • O,O-Diaethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiophosphat [German]
  • O,O-Diethyl 2-isopropyl-4-methylpyrimidyl-6-thiophosphate
  • O,O-Diethyl O-(2-isopropyl-4-methyl-6-pyrimidyl) thionophosphate
  • O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate
  • O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl)phosphorothioate
  • O,O-Diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl)phosphorothioate
  • O,O-Diethyl O-6-methyl-2-isopropyl-4-pyrimidinyl phosphorothioate
  • O,O-Diethyl-O-(2-isopropyl-4-methyl-6-pyrimidinyl)-phosphorothioate
  • O,O-Diethyl-O-(2-isopropyl-4-methyl-6-pyrimidyl)phosphorothioate
  • O,O-Diethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiofosfaat
  • O,O-Diethyl-O-(2-isopropyl-4-methyl-pyrimidin-6-yl)-monothiofosfaat [Dutch]
  • O,O-Dietil-O-(2-isopropil-4-metil-pirimidin-6-il)-monotiofosfato
  • O,O-Dietil-O-(2-isopropil-4-metil-pirimidin-6-il)-monotiofosfato [Italian]
  • O-2-Isopropyl-4-methylpyrimidyl-O,O-diethyl phosphorothioate
  • Oleodiazinon
  • OMS 469
  • Optimizer
  • Phosphorothioate, O,O-diethyl O-6-(2-isopropyl-4-methylpyrimidyl)
  • Phosphorothioic acid, O,O-diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) ester
  • Phosphorothioic acid, O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) ester
  • Phosphorothioic acid, O,O-diethyl O-(isopropylmethylpyrimidinyl) ester
  • PT 265
  • Sarolex
  • Spectracide
  • Srolex
  • Terminator
  • Thiophosphate de O,O-diethyle et de O-2-isopropyl-4-methyl-6-pyrimidyle
  • Thiophosphate de O,O-diethyle et de O-2-isopropyl-4-methyl-6-pyrimidyle [French]
  • Thiophosphoric acid 2-isopropyl-4-methyl-6-pyrimidyl diethyl ester
  • UNII-YUS1M1Q929

Systematic Names

  • Diazinon
  • O,O-Diethyl 2-isopropyl-6-methyl-4-pyrimidinylphosphorothioate
  • Phosphorothioic acid, O,O-diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) ester
  • Phosphorothioic acid, O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) ester

Superlist Names

  • Diazinon
  • Phosphorothioic acid, O,O-diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) ester

Registry Numbers

CAS Registry Number

  • 333-41-5

FDA UNII

  • YUS1M1Q929

Other Registry Numbers

  • 27936-40-9
  • 30583-38-1
  • 65863-03-8

System Generated Number

  • 0000333415

Structure Descriptors

InChI

InChI=1S/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3

InChIKey

FHIVAFMUCKRCQO-UHFFFAOYSA-N

Smiles

CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 2mg/kg (2mg/kg)   Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
chicken LD50 oral 8400ug/kg (8.4mg/kg)   "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.
duck LD50 oral 3500ug/kg (3.5mg/kg)   Down to Earth. Vol. 35, Pg. 25, 1979.
guinea pig LC50 inhalation 5500mg/m3/4H (5500mg/m3)   Proceedings of the European Society for the Study of Drug Toxicity. Vol. 15, Pg. 239, 1974.
guinea pig LD50 oral 250mg/kg (250mg/kg)   "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.
human TDLo oral 214mg/kg (214mg/kg) SKIN AND APPENDAGES (SKIN): SWEATING: OTHER

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: MUSCLE WEAKNESS		 Clinical Toxicology. Vol. 12, Pg. 435, 1978.
mammal (species unspecified) LD50 unreported 76mg/kg (76mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 338, 1971.
mouse LC50 inhalation 1600mg/m3/4H (1600mg/m3)   Proceedings of the European Society for the Study of Drug Toxicity. Vol. 15, Pg. 239, 1974.
mouse LD50 intraperitoneal 33mg/kg (33mg/kg)   Toxicology and Applied Pharmacology. Vol. 2, Pg. 495, 1960.
mouse LD50 intravenous 180mg/kg (180mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00023,
mouse LD50 oral 17mg/kg (17mg/kg)   Shokuhin Eiseigaku Zasshi. Food Hygiene Journal. Vol. 24, Pg. 268, 1983.
mouse LD50 skin 2750mg/kg (2750mg/kg)   Journal of Toxicology and Environmental Health. Vol. 9, Pg. 491, 1982.
mouse LD50 subcutaneous 58mg/kg (58mg/kg)   Osaka Igaku Zasshi. Vol. 71, Pg. 6099, 1959.
pig LD50 oral 320mg/kg (320mg/kg)   Yakkyoku. Pharmacy. Vol. 31, Pg. 459, 1980.
pig LD50 skin 633mg/kg (633mg/kg)   Yakkyoku. Pharmacy. Vol. 31, Pg. 459, 1980.
pigeon LD50 oral 3160ug/kg (3.16mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail LD50 oral 4210ug/kg (4.21mg/kg)   ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
rabbit LD50 oral 143mg/kg (143mg/kg)   Yakkyoku. Pharmacy. Vol. 31, Pg. 459, 1980.
rabbit LD50 skin 3600mg/kg (3600mg/kg)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A131, Pg. 1983,
rat LC50 inhalation 3500mg/m3/4H (3500mg/m3)   Farm Chemicals Handbook. Vol. -, Pg. C101, 1991.
rat LD50 intraperitoneal 65mg/kg (65mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 436, 1955.
rat LD50 intratracheal 210mg/kg (210mg/kg)   JAT, Journal of Applied Toxicology. Vol. 19, Pg. 133, 1999.
rat LD50 oral 66mg/kg (66mg/kg)   Down to Earth. Vol. 35, Pg. 25, 1979.
rat LD50 skin 180mg/kg (180mg/kg)   Proceedings of the Annual Meeting of the New Jersey Mosquito Extermination Association. Vol. -, Pg. 155, 1957.
rat LD50 unreported 250mg/kg (250mg/kg)   Rinsho Shinkeigaku. Clinical Neurology. Vol. 23, Pg. 101, 1983.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
log P (octanol-water) 3.81 (none)   EXP
Water Solubility 40 mg/L 25 EXP
Vapor Pressure 9.01E-05 mm Hg 25 EXP
Henry's Law Constant 1.13E-07 atm-m3/mole 23 EXP
Atmospheric OH Rate Constant 9.67E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.