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Substance Name: Evobrutinib [INN]
RN: 1415823-73-2
UNII: ZA45457L1K
InChIKey: QUIWHXQETADMGN-UHFFFAOYSA-N

Note

  • A selective oral BTK inhibitor that has been shown to inhibit B-cell activation both in vitro and in vivo.

Molecular Formula

  • C25-H27-N5-O2

Molecular Weight

  • 429.5213
 
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Names and Synonyms

Results Name

  • Evobrutinib [INN]

Name of Substance

  • Evobrutinib

Synonyms

  • 1-(4-(((6-Amino-5-(4-phenoxyphenyl)-4-pyrimidinyl)amino)methyl)-1-piperidinyl)-2-propen-1-one
  • 1-(4-((6-Amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino)-methyl)-piperidin-1-yl)-propenone
  • 2-Propen-1-one, 1-(4-(((6-amino-5-(4-phenoxyphenyl)-4-pyrimidinyl)amino)methyl)-1-piperidinyl)-
  • Evobrutinib
  • Evobrutinib [INN]
  • UNII-ZA45457L1K

Registry Numbers

CAS Registry Number

  • 1415823-73-2

FDA UNII

  • ZA45457L1K

System Generated Number

  • 1415823732

Structure Descriptors

InChI

InChI=1S/C25H27N5O2/c1-2-22(31)30-14-12-18(13-15-30)16-27-25-23(24(26)28-17-29-25)19-8-10-21(11-9-19)32-20-6-4-3-5-7-20/h2-11,17-18H,1,12-16H2,(H3,26,27,28,29)

InChIKey

QUIWHXQETADMGN-UHFFFAOYSA-N

Smiles

Nc1ncnc(NCC2CCN(CC2)C(=O)C=C)c1c3ccc(Oc4ccccc4)cc3